- Original Article
- Inhibitory effects of several drugs to intestinal secretory stimulation of heat-labile enterotoxin produced by enterotoxigenic E. coli.
-
Kyung Rae Moon, Sang Kee Park, Young Wook Chun, Kap Seung Kim, Young Bong Park, Young Cheon Na, Jeong Hyung Park, Hyun Kook Lee, Nam Ung Yang
-
Clin Exp Pediatr. 1991;34(9):1231-1239. Published online September 30, 1991
-
|
For exploitation of new antidiarrheal agents to heat-labile enterotoxin (LT) produced by enterotox-
igenic E. coli, we have tested several drugs by rabbit ileal loop assay and obtained some significant
results. L-glutathione (20 mg), P-chloromercuriphenyl sulfonic acid (20 mg) and water heating extract
of Prunus mume (20 mg) reduced LT-mediated intestinal fluid secretion in rabbit ileal loop assay by
92%, 87%, 92% respectively. Maleate,... |
-
-
|